Abstract #3334

Highly-Accelerated, Self-Calibrated Stack-of-Spirals Arterial Spin Labeling Using 3D SPIRiT Reconstruction

Yulin V Chang¹, Marta Vidorreta², Ze Wang³, and John A Detre²

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Neurology, University of Pennsylvania, Philadelphia, PA, United States, ³Hangzhou Normal University, Hangzhou, Zhejiang, China, People's Republic of

3D coverage of the whole brain by using RARE-refocused stack-of-2D-spirals often suffers from low temporal/spatial resolution due to the long spiral readout or long echo train. In this work we present a method that allows whole-brain coverage at 3 mm isotropic spatial resolution with one- or two-segment, accelerated acquisitions in both partition and spiral directions. The technique was applied in conjunction with background-suppressed pCASL, resulting in improved temporal/spatial resolution for quantification of cerebral blood flow.

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