Abstract #3336

Conductivity Determination of Deep Gray Matter Nuclei Utilizing Susceptibility-Based Delineation

Ulrich Katscher¹, Mussa Gagiyev¹, and Jakob Meineke¹

¹Philips Research Europe, Hamburg, Germany

Deep gray matter nuclei (DGMN) in the human brain play an important role for numerous diseases like Alzheimer’s disease. Thus, the characterization of DGMN in the framework of multiple MR-based physiologic parameters (like magnetic susceptibility or electric conductivity) is expected to be helpful for understanding these diseases. This study investigates – to the best of our knowledge, for the first time - the electric conductivity of DGMN in healthy volunteers, reflecting the electrolyte content of these nuclei. Conductivity determination is boosted by utilizing geometry information obtained from susceptibility maps during conductivity reconstruction.

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