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Abstract #3367

Cerebellar surface mapping using T1 and T2* relaxometry at ultrahigh-field MRI: from  macroscale to microscale?

Yohan Boillat1, Pierre-Louis Bazin2, Kieran O'Brien3,4, Mário João Fartaria de Oliveira5,6, Guillaume Bonnier1,6,7, Gunnar Krueger6,8, Wietske van der Zwaag1,9, and Cristina Granziera1,6,7,10

1Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 3Siemens Healthcare Pty Ltd., Brisbane, Australia, 4University of Queensland, St-Lucia, Australia, 5University of Lausanne, Lausanne, Switzerland, 6Advanced Clinical Imaging Technology Group, Siemens, Lausanne, Switzerland, 7Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, 8Healthcare Sector IM&WS S, Siemens Schweiz AG, Lausanne, Switzerland, 9Spinoza Centre for Neuroimaging, Amsterdam, Switzerland, 10Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, United States

The quantitative properties of the cerebellum were assessed by acquiring T1 and T2*contrasts at 7T and mapping these onto the cerebellar cortex. T1 maps showed medial-lateral alternating stripes of different intensities while T2* values were homogeneously distributed across the lobes. This study showed the heterogeneity of the cerebellar cortex in terms of tissue content, which in part parallels a well-established gene expression pattern.

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