Meeting Banner
Abstract #3376

An automated pipeline for mouse brain morphometric MRI

Marco Pagani1,2, Mario Damiano1, Alberto Galbusera1, Sotirios A Tsaftaris3,4, and Alessandro Gozzi1

1Istituto Italiano di Tecnologia, Rovereto, Italy, 2Center for Mind and Brain Sciences, Rovereto, Italy, 3IMT - Institute for Advanced Studies, Lucca, Italy, 4Institute of Digital Communications, School of Engineering, The University of Edinburgh, Edinburgh, United Kingdom

We provide a detailed description of registration-based procedures for voxel based morphometry, cortical thickness estimation and automated anatomical labelling of the mouse brain. To illustrate our procedures, we described their application to quantify morphological differences in two inbred mouse strains characterised by different social behaviour. We show that our approach can reliably detect both focal and large scale gray matter alterations using complementary readouts. The operational workflows described here are expected to help the implementation of rodent morphoanatomical methods by non-expert users, and promote the use of these tools across the preclinical neuroimaging community.

This abstract and the presentation materials are available to members only; a login is required.

Join Here