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Abstract #3451

Investigation of Intravoxel Fiber Configuration Complexity in the Human Heart

Changyu SUN1, Lihui WANG2, Feng YANG3, and Yuemin ZHU1

1CREATIS; CNRS UMR 5220; Inserm U 1044; INSA of Lyon; University of Lyon;, Lyon, France, 2School of computer science and technology, Guizhou University, Guiyang, China, People's Republic of, 3School of Computer and Information Technology, Beijing JiaoTong University, Beijing, China, People's Republic of

Fiber crossing in the myocardium of the heart is controversial despite some reports on the heart of animals. The purpose of this study is to investigate the fiber configuration complexity in a voxel, such as fiber crossing, in the human heart. We applied two different reconstruction techniques commonly used in high angular resolution diffusion imaging (HARDI) to conventional diffusion tensor imaging (DTI) data of the human heart acquired on clinical MRI system. The results consistently demonstrated that the human myocardium exhibits some complex fiber configurations such as fiber crossing in a voxel.

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