Abstract #3580

The Development of Tissue Mimicking Gels

Peter Andrew Hardy¹, Christopher J Norsigian², Walter Witschey³, and Luke H Bradley²

¹Radiology, University of Kentucky, Lexington, KY, United States, ²Anatomy & Neurobiology, University of Kentucky, Lexington, KY, United States, ³Smilow Center for Translational Research, University of Pennsylvania, Philadelphia, PA, United States

Developing tissue mimicking materials can be helpful in reducing the cost and duration of experiments which otherwise require animals. We tested a variety of agarose gels of different gel strength as suitable tissue mimicking material for convection enhanced delivery. The results demonstrate a significant difference in infusion volume and we relate that, through MR measurements, to the mechanical stiffness of the gels.

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