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Abstract #3705

Effect of exposure in hypoxia environment caused by high altitude on magnetic susceptibility in human brain assessed by quantitative susceptibility mapping

Dandan Zheng1, Wenjia Liu2, Bing Wu1, and Lin Ma2

1MR Research China, GE Healthcare, Beijing, China, People's Republic of, 2Radiology Department, Beijing Military General Hospital, Beijing, China, People's Republic of

Cerebrospinal fluid fraction, CBF and T2 decay have been reported to be related with hypoxia caused by high altitude in previous studies. All these biomarkers maybe associate with tissue homogeneous magnetism changes, which may result in the magnetic susceptibility changes. Quantitative susceptibility mapping (QSM) is a novel technique that allows mapping of tissue magnetic susceptibility. It has the potential to be more sensitive with respect to magnetic tissue properties than conventional magnitude-based techniques such as transverse relaxation rates. This study was designed to reveal the effect of exposure in hypoxia environment on magnetic susceptibility in human brain assessed by QSM.

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