Abstract #3711

MRI Assessment of Acute Pathologic Process after Myocardial Infarction: Role of Magnetic Nanoparticle-based MRI

Cheongsoo Park^1,2, Eun-Hye Park³, Jongeun Kang^1,4, Kiyuk Chang³, and Kwan Soo Hong^1,4,5

¹Korea Basic Science Institute, Cheongju, Korea, Republic of, ²The Catholic University of Korea, Seoul, Korea, Republic of, ³Seoul St. Mary’s Hospital and College of Medicine, Seoul, Korea, Republic of, ⁴Chungnam National University, Daejeon, Korea, Republic of, ⁵University of Science and Technology, Daejeon, Korea, Republic of

Myocardial infarction (MI) is the major cause of sudden death in most industrialized society. Imaging of early disease progression and investigation of relationship between myocardial necrosis and successive inflammatory response are needed for optimal treatment of MI. We conducted cardiac MR imaging of disease progression in acute MI by using three different MRI methods of Gd (LGE), Mn (ME), and iron oxide nanoparticles (MNP)-based MRI for estimation of infarcted and inflammatory regions.

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