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Abstract #3737

Functional Resolution of Gradient Echo, Asymmetric Spin Echo, and Spin Echo in Functional MRI

Eun Soo Choi1 and Gary Glover2

1Electrical Engineering, Stanford University, Stanford, CA, United States, 2Radiology, Stanford University, Stanford, CA, United States

In BOLD fMRI, gradient-echo and spin-echo pulse sequences have been widely used due to their higher functional sensitivity and spatial specificity, however, fair comparison between SE and GRE methods has often not been made properly. In this study, we defined "functional resolution" as a quantitative metric to evaluate spatial specificity of BOLD contrast fMRI and measured it in SE, asymmetric spin-echo, and GRE. Then we conducted spatial smoothing to equalize their functional resolution and compare their functional sensitivity under the equivalent conditions.

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