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Abstract #3763

Aberrant functional connectivity of resting state networks in subclinical hypothyroidism

Mukesh Kumar1, Ritu Tyagi1, Prabhjot Kaur1, Subash Khushu1, Maria M D'souza1, Tarun Sekhri2, Ratnesh Kanwar2, and Poonam Rana1

1NMR Research Center, Institute of Nuclear Medicine and Allied Science, Delhi, India, 2Thyroid research centre, Institute of Nuclear Medicine and Allied Science, Delhi, India

Cognitive deficit in Subclinical hypothyroidism (SCH) patient is still a topic to research work upon. The present study was conducted to examine resting state networks (RSNs) in SCH using rsfMRI. SCH patients showed significantly decreased functional connectivity in right fronto-parietal network and anterior default mode network (DMN) as compared with control subjects. Our finding suggests cognitive impairment in resting state networks related to attention and emotional processing in SCH patients

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