Peifang Miao1, Caihong Wang1, Peng Li1, Jingliang Cheng1, Dandan Zheng2, and Zhenyu Zhou2
1MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, People's Republic of, 2GE Healthcare MR Research, Beijing, China, People's Republic of
In order to investigate the cerebral
plasticity in chronic stroke patients well-recovered in global motor function, 29
patients and 30 healthy subjects were recruited to undergo multi-modal MRI
techniques. Group comparisons in gray matter volume(GMV), cerebral blood flow(CBF)
and resting-state functional connectivity(rsFC) were assessed. Compared with
healthy controls, patients exhibited increased GMV in contralesional supplementary motor area,
increased CBFs in contralesional superior frontal gyrus
and supramarginal gyrus, and increased rsFC in contralesional middle temporal gyrus.
The results suggested cerebral structure plasticity, perfusion aberrant and
functional reorganization coexist in well-recovered subcortical stroke
patients, which may underlie functional recovery of stroke patients.