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Abstract #3839

Is fat a confounding factor for MOLLI T1 measurements in the liver at 3 Tesla?

Ferenc E Mozes1, Elizabeth M Tunnicliffe1, Michael Pavlides1,2, and Matthew D Robson1

1RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom, 2Translational Gastroenterology Unit, University of Oxford, Oxford, United Kingdom

The balanced steady-state free precession (bSSFP) sequence at 3T causes water and fat signals to be out of phase when TR=2.3 ms. Since the modified Look-Locker inversion recovery (MOLLI) mapping uses bSSFP readouts, the T1 of voxels that contain both fat and water is influenced by the choice of this TR. Simulations, phantom experiments and measurements collected from patients undergoing bariatric surgery were used to assess the impact of hepatic lipid content on liver MOLLI T1 values.

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