Abstract #3843

Effect of choosing an in-phase vs. a default echo time in 2D MR elastography to estimate hepatic stiffness

Kang Wang¹, William Haufe¹, Nikolaus Szeverenyi¹, Alexandra Schlein ¹, Tanya Wolfson ², Michael S. Middleton¹, Jeffrey Schwimmer³, Kimberley Newton³, Cynthia Behling³, Janis Durelle³, Melissa Paiz³, Jorge Angeles³, Len Lazaro⁴, Diana De La Pena⁴, Carolyn Hernandez⁴, Rohit Loomba ⁴, Meng Yin⁵, Kevin Glaser⁵, Richard Ehman⁵, and Claude Sirlin¹

¹Liver Imaging Group, Department of Radiology, University of California, San Diego, School of Medicine, San Diego, CA, United States, ²Computational and Applied Statistics Laboratory, University of California, San Diego, San Diego, CA, United States, ³Department of Pediatric, University of California, San Diego, San Diego, CA, United States, ⁴NAFLD Translational Research Unit, Division of Gastroenterology, University of California, San Diego, San Diego, CA, United States, ⁵Departments of Radiology, Mayo Clinic, Rochester, MN, United States

To investigate the effect of different echo times (TE) in 2D MR elastography (2D MRE) to estimate hepatic stiffness, two 2D MRE scans were acquired in 50 patients using a 3T GE scanner, one with a default TE value of 20.1 ms (default-TE), and with a nearest in-phase TE value of 20.6 ms (IP-TE). Wave-image quality of each scan was measured quantitatively by ROI size. We demonstrated that 2D MRE with an in-phase TE provides slightly higher wave-image quality in patients with high PDFF, and potentially may be advantageous for fibrosis assessment in NAFLD.

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