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Abstract #3849

Feasibility of Breath-hold Quantitative Susceptibility Mapping on Hepatic Iron quantification

Huimin Lin1, Hongjiang Wei2, Chunlei Liu2, Xu Yan3, Caixia Fu4, and Fuhua Yan1

1Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, People's Republic of, 2Brain Imaging and Analysis Center,Duke University, Durham, NC, United States, 3MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China, People's Republic of, 4Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, People's Republic of

The purpose of this study was to estimate the Quantitative susceptibility mapping (QSM) in hepatic iron evaluation, compared with R2 based Liver concentration estimation (Ferriscan LIC). 7 Patients were scanned on a 1.5 T MR System using a GRE sequence and a SE sequence, for QSM and Ferriscan analysis respectively. QSM algorithm provided susceptibility values estimate. Approximate slices were selected according to the corresponding cross-section on the Ferriscan LIC report. Then ROIs were drawn on QSM images according to LIC maps. Significant positive correlation was observed between QSM and Ferriscan LIC ( R2 = 0.8).

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