Abstract #3910

Racial Differences in Visceral Fat and Hepatic Fat Fraction in Men with HIV, Hepatitis C, or HIV/Hepatitis C Co-infection

Natalie Korn¹, Susan Noworolski¹, Linda Nix², Kyle Tillinghast¹, and Phyllis Tien^3,4

¹Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, ²Northern California Institute for Research and Education, San Francisco, CA, United States, ³University of California, San Francisco, San Francisco, CA, United States, ⁴Department of VA Medical Center, San Francisco, CA, United States

The purpose of this work is to compare differences in visceral fat volume (by IDEAL imaging) and hepatic fat fraction (FF) (by single-voxel MRS) between African American (AA) and Caucasian (CA) men with HIV, HCV, or co-infection (HIV/HCV) against an age-matched control population. We observe AA men to have a trend towards less MR-measured visceral fat and hepatic FF than CA men in a control population. This difference was enhanced and was significant in the HIV population, while there was no observable difference in the HCV or HIV/HCV populations, indicating a need to consider both race and disease status prior to interpretation of visceral or hepatic FF findings.

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