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Abstract #3945

Mapping of sodium and water content ratio in vivo in the human calf

Anja M. Marschar1, Moritz C. Berger1, Mark E. Ladd1, Peter Bachert1, and Armin M. Nagel1,2

1Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Diagnostic and Interventional Radiology, University Medical Center Ulm, Ulm, Germany

Both lower legs of three male healthy volunteers were examined at 3 T and 7 T by means of 1H and 23Na MRI to obtain quantitative maps of the sodium and water content in muscle tissue. Corrections for T2* and T1 relaxation and RF profiles (B1+, B1) were performed. The resulting water content value in calf muscle tissue was in the range of 75–85 mol/l, the level of sodium was 15–21 mmol/l (sodium-to-water content ratio: 0.20–0.27 ‰).

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