Both lower legs of three male healthy volunteers were examined at 3 T and 7 T by means of 1H and 23Na MRI to obtain quantitative maps of the sodium and water content in muscle tissue. Corrections for T2* and T1 relaxation and RF profiles (B1+, B1–) were performed. The resulting water content value in calf muscle tissue was in the range of 75–85 mol/l, the level of sodium was 15–21 mmol/l (sodium-to-water content ratio: 0.20–0.27 ‰).
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