Abstract #3949

A pilot validation of compressed sensing four dimensional multi-echo based echo-planar J-resolved spectroscopic imaging in human brain

Manoj Kumar Sarma¹, Zohaib Iqbal¹, Rajakumar Nagarajan¹, and M. Albert Thomas¹

¹Radiological Sciences, UCLA School of Medicine, Los angeles, Los Angeles, CA, United States

Phase encoded MR spectroscopic imaging (MRSI) is a time-consuming protocol because there is a large number of phase encodings to be collected. Non-uniform undersampling (NUS) and Compressed Sensing (CS), which has been widely used in MRI/MRS can be used to speed up the acquisition further. In this study, we have implemented a novel CS based multi -echo echo planar J-Resolved spectroscopic imaging (ME-EP-JRESI) acquisition and CS reconstruction in in human brain at 3T. We were able to detect and quantify several metabolites using a modified ProFit algorithm. The CS reconstructed spectra were of high quality, with metabolite ratios matching the fully encoded data closely.

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