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Abstract #3949

A pilot validation of compressed sensing four dimensional multi-echo based echo-planar J-resolved spectroscopic imaging in human brain

Manoj Kumar Sarma1, Zohaib Iqbal1, Rajakumar Nagarajan1, and M. Albert Thomas1

1Radiological Sciences, UCLA School of Medicine, Los angeles, Los Angeles, CA, United States

Phase encoded MR spectroscopic imaging (MRSI) is a time-consuming protocol because there is a large number of phase encodings to be collected. Non-uniform undersampling (NUS) and Compressed Sensing (CS), which has been widely used in MRI/MRS can be used to speed up the acquisition further. In this study, we have implemented a novel CS based multi -echo echo planar J-Resolved spectroscopic imaging (ME-EP-JRESI) acquisition and CS reconstruction in in human brain at 3T. We were able to detect and quantify several metabolites using a modified ProFit algorithm. The CS reconstructed spectra were of high quality, with metabolite ratios matching the fully encoded data closely.

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