Abstract #3951

2D MR Spectroscopic Imaging of the Pediatric Brain using Compressed Sensing

Rohini Vidya Shankar¹, Houchun Harry Hu², John C Chang³, and Vikram D Kodibagkar¹

¹Biomedical Engineering, Arizona State University, Tempe, AZ, United States, ²Radiology, Phoenix Children's Hospital, Phoenix, AZ, United States, ³Banner MD Anderson Cancer Center, Gilbert, AZ, United States

The spatial variations in brain metabolite concentrations can be mapped using magnetic resonance spectroscopic imaging (MRSI). The long scan times in MRSI do not permit its inclusion in pediatric imaging protocols. MRSI accelerated by compressed sensing was used to image the pediatric brain for various acceleration factors 2X-5X. The retrospectively undersampled reconstructions showed high data fidelity for up to 80% undersampling when compared with the fully sampled reference dataset. Studies are underway to prospectively acquire and validate CS accelerated MRSI data in pediatric patients.

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