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Abstract #3981

31P MRS Signal-to-Noise Ratio in Human Brain at 3, 7, and 9.4 Tesla Using Dual Tuned Head RF Coils

Marek Chmelik1,2, Diana Bencikova3, Christian Mirkes4, Christopher T. Rodgers5, Gunamony Shajan4, Klaus Scheffler4,6, Siegfried Trattnig1,2, and Wolfgang Bogner1

1High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 3Department of Nuclear Physics and Biophysics, Faculty of Mathematics, Physics and Informatics, Comenius University, Bratislava, Slovakia, 4High-Field MR Center, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 5OCMR, RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom, 6Department for Biomedical Magnetic Resonance, University of Tuebingen, Tuebingen, Germany

The purpose of this study was to quantitatively compare the SNR of brain 31P-MRS coils capable of covering the whole brain at various B0 field strenghts. SNR was compared using phantoms and in vivo in clinically acceptable measurement times at 3T (birdcage), 7T (23ch-array) and 9.4T (27ch-array). Data showed approximately 3-fold higher SNR at 7T than at 3T. 9.4T provided an additional -more than linear- increase. WSVD coil combination outperformed Brown’s coil combination. Especially with the 7T coil the necessity of advanced coil combination algorithms is apparent.

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