Abstract #3981

31P MRS Signal-to-Noise Ratio in Human Brain at 3, 7, and 9.4 Tesla Using Dual Tuned Head RF Coils

Marek Chmelik^1,2, Diana Bencikova³, Christian Mirkes⁴, Christopher T. Rodgers⁵, Gunamony Shajan⁴, Klaus Scheffler^4,6, Siegfried Trattnig^1,2, and Wolfgang Bogner¹

¹High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ³Department of Nuclear Physics and Biophysics, Faculty of Mathematics, Physics and Informatics, Comenius University, Bratislava, Slovakia, ⁴High-Field MR Center, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, ⁵OCMR, RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom, ⁶Department for Biomedical Magnetic Resonance, University of Tuebingen, Tuebingen, Germany

The purpose of this study was to quantitatively compare the SNR of brain ³¹P-MRS coils capable of covering the whole brain at various B₀ field strenghts. SNR was compared using phantoms and in vivo in clinically acceptable measurement times at 3T (birdcage), 7T (23ch-array) and 9.4T (27ch-array). Data showed approximately 3-fold higher SNR at 7T than at 3T. 9.4T provided an additional -more than linear- increase. WSVD coil combination outperformed Brown’s coil combination. Especially with the 7T coil the necessity of advanced coil combination algorithms is apparent.

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