Nicole D Fichtner1,2, Ioannis Giapitzakis3, Nikolai Avdievich3, Anke Henning2,3, and Roland Kreis1
1Depts. Radiology and Clinical Research, University of Bern, Bern, Switzerland, 2Institute for Biomedical Engineering, UZH and ETH Zurich, Zurich, Switzerland, 3Max Planck Institute for Biological Cybernetics, Tuebingen, Germany
Ultra high field
strengths offer the benefit of higher signal to noise ratio as well as improved
separation of metabolites in spectroscopy, which is beneficial for evaluating downfield
peaks. In the current work, the metabolite cycling technique is implemented at
9.4T in order to evaluate the downfield part of the human brain spectrum. The
9.4T spectra confirm the 3T findings on exchanging peaks, and indicate that the
higher field strength improves metabolite separation, allowing for better
quantification of exchanging peaks, which
is also of great interest for chemical exchange dependent saturation transfer
experiments.
