In this study the decoupling efficiency of in vivo 13C MRS measurements of glycogen levels was assessed. Due to SAR restrictions and surface coil decoupling field inhomogeneity, this study showed that short TR coupled spectroscopy provides improved SNR and better defined spectral parameters for fitting, whereas decoupled spectra reduces the number of averages in the same timeframe and runs the risk of varying residual coupling constants across a large field of view with inhomogeneous B2
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