Sneha Pandya1, Yan Zhang1, Thanh Nguyen1, Yi Wang1, Susan A Gauthier2, and Sneha Pandya1
1Department of Radiology, Weill Cornell Medicine, New York, NY, United States, 2Department of Neurology, Weill Cornell Medicine, New York, NY, United States
MRI-derived measures of
lesion accrual and tissue loss have acquired a central role in the
understanding of MS disease evolution, pathogenesis of symptoms, and prediction
of clinical outcome. Conventional MRI imaging is highly sensitive for detection
of MS lesions, which are characteristically hyperintense on a T2 weighted
images, however this technique lacks pathological specificity. QSM can help identify
myelin and iron content changes during an MS lesion’s lifetime.
