Abstract #4123

Magnetic Resonance imaging features of normal and abnormal fetal Ganglionic Eminence. A pictorial essay.

Giorgio Conte^1,2, Claudia Cesaretti¹, Giana Izzo¹, Cecilia Parazzini¹, and Andrea Righini¹

¹Radiology and Neuroradiology, Children's Hospital V. Buzzi, Milan, Italy, ²Radiology Institute, University of Milan, Milan, Italy

Ganglionic eminence (GE) is the main proliferative structure of the ventral telencephalon and contributes to GABA-ergic cortical interneuron population; GE imaging characterization in normal and abnormal conditions is poor. After searching a 3500 cases fetal MR database, we illustrate normal GE features, its abnormalities and its possible associations. GE malformations are divided: 1) bilateral symmetric cavitations as inverted C shape separating GE from parenchyma; 2) GE volume increase associated or not with the above mentioned cavitation. About half of cases are associated with micro-lissencephaly, the others with minor-moderate anomalies. As group apart are presented clastic GE lesions, featuring haemorrhagic changes.

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