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Abstract #4124

Magnetic Resonance Imaging of hippocampal subfield in a large sample of posttraumatic stress disorder

Lianqing Zhang1, Xingyu Hu1, Shiguang LI2, Lei Li 1, Lizhou Chen1, Qi Liu1, Lu Lu1, Qiyong Gong1, and Xiaoqi Huang1

1Huaxi MR Research Center (HMRRC), radiology department, West China Hospital of Sichuan University, Chengdu, China, People's Republic of, 2radiology department, The First People's Hospital of Zunyi, Zunyi, China, People's Republic of

We analysis hippocampal subfields volume changes in a relatively large sample of adult patients with post-traumatic stress disorder and same stressor event survivors using an automatically segmentation protocol. Our findings provided evidence that the responsive change of hippocampus after stress which cause cellular edema or at a early stage of the disorder. The second find is the difference between genders referring to the role of hippocampus in PTSD etiology. Male patients seem to be more likely affected in right hippocampus while in female patients, left hippocampus seems contributed more.

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