Abstract #4126

Functional Disconnectivity in Schizophrenia Patients with Auditory Hallucinations: a Dynamic Resting-State Functional MRI Study with a Multiband EPI Sequence

Wenjing Zhang¹, Wei Deng², Siyi Li¹, John Sweeney³, Qiyong Gong¹, and Su Lui¹

¹Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, China, People's Republic of, ²Department of Psychiatry, West China Hospital of Sichuan University, Chengdu, China, People's Republic of, ³Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, United States

A simultaneous multi-slice multiband EPI sequence, which could significantly increase temporal resolution for the fMRI scanning, was adopted to investigate the dynamic functional connectivity in the schizophrenia patients with auditory hallucinations. We found that, relative to traditional static functional connectivity calculation, dynamic analysis evaluated with multiband EPI provides much more information, including more widespread aberrant functional connectivity maps across different states and their temporal variability over time. The expanded information may help to give better insight into the pathological processes and subsequently reveal the spontaneous model of affected networks in schizophrenia.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.