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Abstract #4160

Neurochemical alterations detected in Irritable Bowel Syndrome using 2D L-COSY

Scott Quadrelli1,2, Gerald Holtmann3, Nicholas Talley2, Saadallah Ramadan2, and Carolyn Mountford4

1Queensland University of Technology, Brisbane, Australia, 2The University of Newcastle, Newcastle, Australia, 3The University of Queensland, Brisbane, Australia, 4Translational Research Institute, Brisbane, Australia

IBS is a characterised intermittent chronic abdominal pain and altered bowel habit in the absence of an organic cause. Neurochemical changes may play a role in the pathophysiology of IBS.

Our pilot studies indicate that in vivo neuro 2D L-COSY monitors alterations to neurochemical pathways associated with IBS.

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