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Abstract #4192

Diffusion kurtosis imaging can efficiently assess the glioma grade, cellular proliferation and survival

Rifeng Jiang1, Jingjing Jiang1, Jingjing Shi1, Yihao Yao1, Nanxi Shen1, Changliang Su1, Ju Zhang1, and Wenzhen Zhu1

1Radiology, Tongji Hospital, Wuhan, China, People's Republic of

Compared with conventional diffusion metrics, the kurtosis metrics derived from DKI in the solid region of the tumors were better diagnostic factors in distinguishing HGGs from LGGs and identifying grade II, III and IV gliomas. The kurtosis metrics offered great potential to noninvasively predict the cellular proliferation of gliomas. DKI was also useful to evaluate the survival of glioma patients, and MK was a significant death risk in glioma patients.

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