Meeting Banner
Abstract #4193

Comparison of ferumoxytol and gadolinium enhancement changes in response to Avastin in high grade glioma patients

Andrea Horváth1,2,3, Csanád Várallyay1, Daniel Schwartz1, Prakash Ambady1, Péter Bogner4, and Edward Neuwelt1

1Department of Neurology, Oregon Health and Science University, Portland, OR, United States, 2Department of Neurosurgery, University of Pécs, Pécs, Hungary, 3Diagnsotic Center of Pécs, Pécs, Hungary, 4Department of Radiology, University of Pécs, Pécs, Hungary

Ferumoxytol is an alternative, investigational, iron-based MRI contrast agent, which might be beneficial in the accurate diagnosis of treated glioma patients. In this study we investigated how gadolinium and 24 hour ferumoxytol enhancement change as a result of Avastin treatment. The enhancement volumes and normalized signal intensities before and after Avastin treatment were calculated with histogram analysis and were compared between contrast agents. Changes in enhancement volumes and in signal intensities in response to Avastin were not different between contrast agents. Ferumoxytol shows good potential in brain tumor imaging.

This abstract and the presentation materials are available to members only; a login is required.

Join Here