Abstract #4194

Application of diffusion kurtosis imaging for a structural differentiation of the brain metastasis and primary glioblastomas

Aram Tonoyan¹, Ezequiel Farrher², Ivan Maximov³, Farida Grinberg^4,5, Elena Lyubimova⁶, Ludmila Fadeeva¹, Eduard Pogosbekyan¹, Nadim Joni Shah^2,5, and Igor Pronin¹

¹Neuroimaging, Burdenko Neurosurgery Institute, Moscow, Russian Federation, ²Institute of Neuroscience and Medicine – 4, Medical Imaging Physics, Forschungszentrum Juelich GmbH, Juelich, Germany, ³Experimental physics III, TU Dortmund University, Dortmund, Germany, ⁴Institute of Neuroscience and Medicine – 4, Medical Imaging Physics, Forschungszentrum Juelich GmbH, Julich, Germany, ⁵Faculty of Medicine, Department of Neurology, RWTH Aachen University, JARA, Aachen, Germany, ⁶Radiology, Krasnodar Regional Hospital, Krasnodar, Russian Federation

MRI allows one to detect and visualize the primary and metastatic tumours in the brain. However, conventional methods suffer from a poor contrast. In turn, it leads to a problem in proper diagnostics of the tumour origins. In the present work we demonstrated the potential of kurtosis imaging technique in the tumour differentiation of primary tumour and metastasis cancers.

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