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Abstract #4194

Application of diffusion kurtosis imaging for a structural differentiation of the brain metastasis and primary glioblastomas

Aram Tonoyan1, Ezequiel Farrher2, Ivan Maximov3, Farida Grinberg4,5, Elena Lyubimova6, Ludmila Fadeeva1, Eduard Pogosbekyan1, Nadim Joni Shah2,5, and Igor Pronin1

1Neuroimaging, Burdenko Neurosurgery Institute, Moscow, Russian Federation, 2Institute of Neuroscience and Medicine – 4, Medical Imaging Physics, Forschungszentrum Juelich GmbH, Juelich, Germany, 3Experimental physics III, TU Dortmund University, Dortmund, Germany, 4Institute of Neuroscience and Medicine – 4, Medical Imaging Physics, Forschungszentrum Juelich GmbH, Julich, Germany, 5Faculty of Medicine, Department of Neurology, RWTH Aachen University, JARA, Aachen, Germany, 6Radiology, Krasnodar Regional Hospital, Krasnodar, Russian Federation

MRI allows one to detect and visualize the primary and metastatic tumours in the brain. However, conventional methods suffer from a poor contrast. In turn, it leads to a problem in proper diagnostics of the tumour origins. In the present work we demonstrated the potential of kurtosis imaging technique in the tumour differentiation of primary tumour and metastasis cancers.

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