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Abstract #4206

On-scanner sparse sampling for high resolution structural imaging of the human brain at 7T

Matthan W.A. Caan1,2, Abdallah G. Motaal1, Bram F. Coolen1, Wouter V. Potters1, Kerry Zhang1, Pieter Buur2, and Aart J. Nederveen1

1Radiology, Academic Medical Center, Amsterdam, Netherlands, 2Spinoza Centre for Neuroimaging, Amsterdam, Netherlands

We aimed to increase spatial resolution while maintaining scanning time for 3D-T1 weighted imaging by on-scanner undersampling at 7T. A 3DT1-weighted structural scan with a resolution of 0.5 mm3 was acquired with 4 times variable poisson disc compressed sensing (CS) undersampling. For comparison, scans with resolutions of 0.5 and 0.7 mm3 were acquired, with SENSE undersampling adapted to match scanning time.The CS-reconstructed scan showed no streaking artifacts, was less hampered by noise in deep brain regions, had better contrast between gray matter and CSF and less partial voluming effects.

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