Meeting Banner
Abstract #4325

Automatic organ-specific localization and quantification of fat in abdominal chemical shift encoding-based water-fat MRI: application to weight-loss in obesity

Jun Shen1, Thomas Baum2, Christian Cordes2, Beate Ott3, Claudia Eichhorn3, Thomas Skurk3,4, Hendrik Kooijman5, Ernst J Rummeny2, Hans Hauner3,4, Bjoern H Menze1, and Dimitrios C Karampinos2

1Department of Computer Science, TU Munich, Munich, Germany, 2Department of Radiology, TU Munich, Munich, Germany, 3Else Kröner Fresenius Center for Nutritional Medicine, TU Munich, Munich, Germany, 4ZIEL Research Center for Nutrition and Food Sciences, TU Munich, Munich, Germany, 5Philips Healthcare, Hamburg, Germany

The accumulation and regional distribution of abdominal adipose tissue and organ fat plays an important role in several diseases including obesity, metabolic syndrome and diabetes. The present work proposes a fully automatic method for abdominal organ segmentation and adipose tissue classification and measurement based on chemical shift encoding-based water-fat MR images. The results from the automatic method showed very good agreement with the manually created references. The developed automatic algorithm allowed the detection of regional differences in changes of adipose tissue depots in a study of 20 obese women undergoing a calorie restriction intervention.

This abstract and the presentation materials are available to members only; a login is required.

Join Here