Abstract #4351

Characterizing metabolic profiles in non-enhancing gliomas using 3D MRSI

Yan Li¹, Tracy L Luks¹, Jason C Crane¹, Sarah J Nelson¹, and Tracy R McKnight²

¹Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, United States, ²Tobacco-Related Disease Research Program, University of California, Oakland, CA, United States

This study evaluated the metabolite profiles that were acquired using short and long echo time (TE) magnetic resonance spectroscopic imaging (MRSI) for forty patients with non-enhancing gliomas, including 25 grade 2 and 15 grade 3 gliomas. Metabolite differences were detected between the lesions and white matter, as well as between grades. There were also differences in the T2 values between metabolites within the lesions that could influence the Cho/NAA ratios between short and long TE MRSI.

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