Abstract #4382

Functional Reorganization of the Brain in Ischemic Stroke Patients after the Repetitive Transcranial Magnetic Stimulation: a fMRI Study

Jing Li¹, Xuewei Zhang², Jie Lu¹, Zhentao Zuo³, Rong Xue³, Yong Fan⁴, Yuzhou Guan⁵, and Weihong Zhang¹

¹Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China, People's Republic of, ²Department of Interventional Radiology, China Meitan General Hospital, Beijing, China, People's Republic of, ³State Key Laboratory of Brain and Cognitive Science, Beijing MR Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, People's Republic of, ⁴Department of Radiology, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, ⁵Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China, People's Republic of

It is a resting-state fMRI( rs-fMRI) study of patients with motor disturbance after acute ischemic stroke. We assessed the functional connectivity (FC) changes of the ipsilesional primary motor cortex (M1) within the brain before and after the repetitive transcranial magnetic stimulation (rTMS) by rs-fMRI. The research not only gave theoretical support of the rTMS treatment in stroke patients but also investigated the cerebral functional changes in motor recovery.

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