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Abstract #4407

Correlation of DTI Metrics to Spinal Cord Cross Sectional Area in Pediatric Subjects with Spinal Cord Injury

Devon M Middleton1, Shiva Shahrampour1, Scott H Faro1, Sona Saksena2, Mahdi Alizadeh1, Chris J Conklin2, Winston Liu3, Govind Nair4, Laura Krisa2, MJ Mulcahey2, and Feroze B Mohamed2

1Temple University, Philadelphia, PA, United States, 2Thomas Jefferson University, Philadelphia, PA, United States, 3University of Maryland, College Park, MD, United States, 4National Institutes of Health, Bethesda, MD, United States

As more advanced imaging techniques are used for the spinal cord (such as DTI) it is important to examine potential relationships to other injury biomarkers. This study was to examine correlations between DTI metrics and spinal cord cross sectional area in pediatric subjects with spinal cord injury. Cord cross section data was acquired using a recently developed technique for semi-automated spinal cord segmentation and measurement of spinal cord cross sectional area. Fractional anisotropy was found to be strongly significantly correlated with spinal cord cross sectional area in the injured subjects.

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