Abstract #4407

Correlation of DTI Metrics to Spinal Cord Cross Sectional Area in Pediatric Subjects with Spinal Cord Injury

Devon M Middleton¹, Shiva Shahrampour¹, Scott H Faro¹, Sona Saksena², Mahdi Alizadeh¹, Chris J Conklin², Winston Liu³, Govind Nair⁴, Laura Krisa², MJ Mulcahey², and Feroze B Mohamed²

¹Temple University, Philadelphia, PA, United States, ²Thomas Jefferson University, Philadelphia, PA, United States, ³University of Maryland, College Park, MD, United States, ⁴National Institutes of Health, Bethesda, MD, United States

As more advanced imaging techniques are used for the spinal cord (such as DTI) it is important to examine potential relationships to other injury biomarkers. This study was to examine correlations between DTI metrics and spinal cord cross sectional area in pediatric subjects with spinal cord injury. Cord cross section data was acquired using a recently developed technique for semi-automated spinal cord segmentation and measurement of spinal cord cross sectional area. Fractional anisotropy was found to be strongly significantly correlated with spinal cord cross sectional area in the injured subjects.

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