Abstract #4416

Gender-specific attention system subnetwork vulnerability in prematurely born children

Elda Fischi-Gomez^1,2, Lana Vasung¹, Sebastien Urben^3,4, Cristina Borradori-Tolsa¹, François Lazeyras⁵, Jean-Philippe Thiran^2,6, and Petra Susan Hüppi¹

¹Division of Development and Growth. Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland, ²Signal Processing Laboratory 5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ³Child Clinical Neuropsychology Unit, Department of Psychology, University of Geneva, Geneva, Switzerland, ⁴Research Unit, University Service of Child and Adolescent Psychiatry, Department of Psychiatry, University Hospital of Lausanne (CHUV), Lausanne, Switzerland, ⁵Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland, ⁶Department of Radiology, University Hospital Center (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland

Within preterm-born children, being born male and at a lower gestational age have both been associated with a heightened risk for developmental difficulties. However, in this population little is known about the combined effect and the influence of these risk factors on the structural networks subserving attention and executive. Using a diffusion-based brain connectome approach, in this work we analyze the effect of these two factors in the brain networks of school-age preterm born children and provide evidence of a gender-specific vulnerability in the executive attentional subnetwork.

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