Abstract #4426

Distortion correction of fetal EPI using registration of orthogonal stacks with Laplacian constraint

Maria Kuklisova Murgasova¹, Georgia Lockwood Estrin¹, Rita G. Nunes^1,2, Mary Rutherford¹, and Jo Hajnal¹

¹King's College London, London, United Kingdom, ²Instituto de Biofisica e Engenharia Biomedica, Faculdade de Ciencias, Universidade de Lisboa, Lisbon, Portugal

We present a novel method for correction of geometric distortions induced by static B0 field in fetal EPI. The method estimates distortion by including a distortion-correction step in the slice to volume reconstruction of orthogonal EPI stacks with orthogonal phase encoding directions, in the form of non-rigid registration with a Laplacian constraint. We show that the proposed method achieves better consistency with reconstructed ssFSE volumes than EPI volumes constructed from data corrected by B0 field map. The registration-based distortion correction is thus a viable alternative to acquisition of B0 field map.

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