Abstract #4484

Multiparametric quantitative MRI of cartilage composition and bone blood perfusion applied in a case-control study of patellofemoral pain.

Rianne A van der Heijden^1,2, Dirk HJ Poot^1,3,4, Melek Ekinci², Esther E Bron^1,4, Jasper van Tiel^1,5, Stefan Klein^1,4, Peter LJ van Veldhoven⁶, Gabriel P Krestin¹, Jan AN Verhaar⁵, Sita MA Bierma-Zeinstra^2,5, Marienke van Middelkoop², and Edwin HG Oei¹

¹Radiology, Erasmus University Medical Center, Rotterdam, Netherlands, ²General Practice, Erasmus University Medical Center, Rotterdam, Netherlands, ³Imaging Science and Technology, Delft University of Technology, Delft, Netherlands, ⁴Medical informatics, Erasmus University Medical Center, Rotterdam, Netherlands, ⁵Orthopedics, Erasmus University Medical Center, Rotterdam, Netherlands, ⁶Sports medicine, MC Haaglanden, Leidschendam, Netherlands

Diminished patellofemoral cartilage composition and vascular problems are potential pathogenic mechanisms in patellofemoral pain (PFP). These mechanisms can be studied in depth using advanced MRI techniques. We are the first to successfully apply a wide range of quantitative MRI techniques for cartilage composition and bone blood perfusion in a case-control study on PFP. The results show no significant differences in patellofemoral cartilage composition and patellar bone blood perfusion between PFP patients and healthy controls.

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