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Abstract #4484

Multiparametric quantitative MRI of cartilage composition and bone blood perfusion applied in a case-control study of patellofemoral pain.

Rianne A van der Heijden1,2, Dirk HJ Poot1,3,4, Melek Ekinci2, Esther E Bron1,4, Jasper van Tiel1,5, Stefan Klein1,4, Peter LJ van Veldhoven6, Gabriel P Krestin1, Jan AN Verhaar5, Sita MA Bierma-Zeinstra2,5, Marienke van Middelkoop2, and Edwin HG Oei1

1Radiology, Erasmus University Medical Center, Rotterdam, Netherlands, 2General Practice, Erasmus University Medical Center, Rotterdam, Netherlands, 3Imaging Science and Technology, Delft University of Technology, Delft, Netherlands, 4Medical informatics, Erasmus University Medical Center, Rotterdam, Netherlands, 5Orthopedics, Erasmus University Medical Center, Rotterdam, Netherlands, 6Sports medicine, MC Haaglanden, Leidschendam, Netherlands

Diminished patellofemoral cartilage composition and vascular problems are potential pathogenic mechanisms in patellofemoral pain (PFP). These mechanisms can be studied in depth using advanced MRI techniques. We are the first to successfully apply a wide range of quantitative MRI techniques for cartilage composition and bone blood perfusion in a case-control study on PFP. The results show no significant differences in patellofemoral cartilage composition and patellar bone blood perfusion between PFP patients and healthy controls.

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