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Abstract #0027

Detection of intracranial vessel wall lesions using 7T MRI: patients with posterior circulation ischemia versus healthy controls

Anita A. Harteveld1, Anja G. van der Kolk1, H. Bart van der Worp2, Nikki Dieleman1, Peter R. Luijten1, Jaco J.M. Zwanenburg1, and Jeroen Hendrikse1

1Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 2Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, Netherlands

In this study presence and distribution of vessel wall lesions within the intracranial arteries of patients with recent posterior circulation ischemia and matched asymptomatic volunteers were assessed, using intracranial vessel wall MRI at 7T. Overall, vessel wall lesion presence and distribution were comparable between both groups. On arterial segment level, patients showed significantly higher lesion burden in the posterior cerebral artery, suggesting an association between posterior circulation lesion burden and ischemic events. Furthermore, a large amount of lesions showed contrast-enhancement, while the percentage of enhancing lesions was highest in the posterior circulation of the patient group.

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