Abstract #0041

Early Gradual Assessment of Tissue Injury and Functional Outcome after Myocardial Infarction by Cardiovascular Magnetic Resonance T1 Mapping

Sebastian Maximilian Haberkorn^1,2, Christoph Jacoby¹, Jürgen Schrader^2,3, Malte Kelm^1,3, and Uli Flögel^2,3

¹Department of Cardiology, University Hospital Duesseldorf, Duesseldorf, Germany, ²Department of Molecular Cardiology, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany, ³Cardiovascular Research Institute Duesseldorf, Heinrich-Heine University, Duesseldorf, Germany

The value of CMR to distinguish between the severity of ischemic injuries after myocardial (MI) has yet to be established. Here, we quantified local tissue injuries and their correlation with functional outcome in two different experimental models of MI including native and post-contrast T1 maps, T2 maps and LGE. Only native T1 maps enabled in the acute phase after MI the detection of substantial differences in myocardial tissue texture between the two models, where neither of the other measures was indicative. In conclusion, native T1 mapping enables a gradual assessment of myocardial injury and holds predictive potential for the functional outcome.

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