Abstract #0055

Evaluation of Myelin Damage in Diffuse Traumatic Brain Injury using ViSTa-MWI

Joon Yul Choi¹, Ji-Won Baek¹, Jongho Lee¹, and Junghoon Kim^2,3

¹Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, ²CUNY School of Medicine, The City College of New York, New York, NY, United States, ³Moss Rehabilitation Research Institute, Elkins Park, PA, United States

This study investigated myelin damage in subacute moderate to severe TBI using ViSTa-MWI. The results showed widespread reductions of MWF in patients, consistent with pathology involving diffuse axonal injury. Furthermore, the extent of myelin damage was strongly correlated with measures of injury severity and cognitive impairment, demonstrating its clinical relevance.

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