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Abstract #0064

Toward interrogating relationships between grey and white matter measures using Fixel Track-Weighted Imaging and Fixel-Based Analysis

Robert E Smith1, David Raffelt1, David N Vaughan1,2, Fernando Calamante1,3, and Alan Connelly1,3

1The Florey Institute of Neuroscience and Mental Health, Heidelberg, Australia, 2Department of Neurology, Austin Health, Melbourne, Australia, 3Department of Medicine (AH/NH), The University of Melbourne, Australia

Neuroimaging studies assessing white and grey matter are most typically performed as independent analyses. The relationships between white and grey matter abnormalities are therefore poorly understood. We present a novel framework for interrogating relationships between quantitative measures derived from grey matter analysis, and diffusion MRI-based, fibre-specific white matter measures.

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