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Abstract #0068

Single Breath-hold Abdominal T1 Mapping using 3-D Cartesian Sampling and Spatiotemporally Constrained Reconstruction

Felix Lugauer1, Jens Wetzl1, Christoph Forman2, Manuel Schneider1, Berthold Kiefer2, Dominik Nickel2, and Andreas Maier1

1Pattern Recognition Lab, Department of Computer Science, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, 2MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Volumetric T1 mapping in the abdomen is desirable for whole liver assessment of hepatic diseases. In case of breath-hold imaging, accurate but time-consuming methods that sample the relaxation curve (IR or Look-Locker) are restricted to few slices only. To address these limitations, sparse Cartesian sampling with spatiotemporal incoherence is utilized to render 3-D Look-Locker within a single breath-hold possible. We demonstrate feasibility in both phantom and in-vivo measurements. The proposed method shows high agreement with a 2-D reference acquisition and enables an accurate mapping for a wide T1 range, including very low values due to its high temporal resolution.

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