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Abstract #0070

Ultrafast T2 mapping using echo-split GRASE acquisition and parametric POCSMUSE reconstruction

Mei-Lan Chu1,2, Hing-Chiu Chang3, Koichi Oshio4, and Nan-kuei Chen1,2

1Department of Biomedical Engineering, University of Arizona, Tucson, AZ, United States, 2Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, United States, 3Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, 4Department of Diagnostic Radiology, Keio University School of Medicine, Japan

Our novel ultrafast T2 mapping framework, which uniquely integrates echo-split GRASE acquisition and parametric POCSMUSE reconstruction, has the following major advantages. First, parametric T2 map and high-quality multi-contrast images can be derived from a single set of single-shot GRASE data, with inherently low susceptibility to motion artifacts. Second, contamination of stimulated and other high order echoes is minimized in the echo-split GRASE scans. Third, T2 relaxation times can be accurately measured by the parametric POCSMUSE algorithm, which incorporates multiplexed parallel MR reconstruction and multi-echo-pathway signal modeling into a unified procedure.

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