Abstract #0070

Ultrafast T2 mapping using echo-split GRASE acquisition and parametric POCSMUSE reconstruction

Mei-Lan Chu^1,2, Hing-Chiu Chang³, Koichi Oshio⁴, and Nan-kuei Chen^1,2

¹Department of Biomedical Engineering, University of Arizona, Tucson, AZ, United States, ²Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, United States, ³Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, ⁴Department of Diagnostic Radiology, Keio University School of Medicine, Japan

Our novel ultrafast T2 mapping framework, which uniquely integrates echo-split GRASE acquisition and parametric POCSMUSE reconstruction, has the following major advantages. First, parametric T2 map and high-quality multi-contrast images can be derived from a single set of single-shot GRASE data, with inherently low susceptibility to motion artifacts. Second, contamination of stimulated and other high order echoes is minimized in the echo-split GRASE scans. Third, T2 relaxation times can be accurately measured by the parametric POCSMUSE algorithm, which incorporates multiplexed parallel MR reconstruction and multi-echo-pathway signal modeling into a unified procedure.

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