Abstract #0099

Histogram analysis of intravoxel incoherent motion MRI in predicting chemoradiotherapy response in cervical cancer

Jose Angelo Udal Perucho¹, Elaine Yuen Phin Lee¹, Wing Chi Lawrence Chan², Nanjie Gong³, and Queenie Chan⁴

¹Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong, ²Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, ³University of California, Berkeley, CA, United States, ⁴Philips Healthcare, Hong Kong, Hong Kong

Histogram analysis of intravoxel incoherent motion (IVIM) diffusion-weighted MRI (DWI) could be a promising quantitative approach in predicting tumour response to chemoradiotherapy (CRT) in cervical cancer. We retrospectively studied twenty-five patients with cervical cancer who had paired IVIM MRI examinations before and at week-4 of treatment. We observed that histogram skewness of true diffusion coefficient (D) prior to treatment and that a large increase in the 90th percentile of D following CRT were predictive of better CRT response.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.