Abstract #0120

Quantification of short-T2* Signal Components in the Liver using Radial 3D UTE Chemical Shift-Encoded MRI

Ante Zhu^1,2, Diego Hernando^2,3, Kevin M. Johnson^2,3, and Scott B. Reeder^1,2,3,4,5

¹Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁴Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁵Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Recent studies have suggested the presence of a short-T2* signal component in the liver. The origin and MR properties of this signal have not been determined but have been shown to confound the liver fat quantification when using short echo times. In this work, we developed a UTE chemical shift-encoded MRI technique and a multi-component reconstruction to characterize short-T2* liver signals. A short-T2* signal fraction of 11.6±2.4% with an R2* of 2222±281s^-1 was measured in seven healthy volunteers. This study demonstrated the presence of the short-T2* signal component in healthy livers and provided an initial estimate to guide future studies.

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