Abstract #0123

Liver Fat Reduction Following Bariatric Weight Loss Surgery is Greater in the Right Lobe of the Liver

Soudabeh Fazeli Dehkordy¹, Tanya Wolfson², Cheng William Hong¹, Alexandra Schlein¹, Yesenia Covarrubias¹, Jennifer Cui¹, Ethan Z Sy¹, Adrija Mamidipalli¹, Gavin Hamilton¹, Scott B Reeder³, and Claude B Sirlin¹

¹Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, United States, ²Computational and Applied Statistics Laboratory, University of California San Diego, San Diego, CA, United States, ³Department of Radiology, Medical Physics, Biomedical Engineering, Medicine, and Emergency Medicine, University of Wisconsin Madison, Madison, WI, United States

As liver fat is heterogeneously distributed, longitudinal changes in liver fat may vary between liver segments. We used confounder-corrected chemical-shift-encoded MRI to examine longitudinal changes in proton density fat fraction (PDFF) of individual liver segments in obese adults following a weight-loss program comprising a very low calorie diet (VLCD) followed by bariatric weight loss surgery (WLS). We observed that changes in PDFF in the 5-month postoperative period vary across segments, with right-lobe segments having more rapid reduction in liver fat.

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