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Abstract #0123

Liver Fat Reduction Following Bariatric Weight Loss Surgery is Greater in the Right Lobe of the Liver

Soudabeh Fazeli Dehkordy1, Tanya Wolfson2, Cheng William Hong1, Alexandra Schlein1, Yesenia Covarrubias1, Jennifer Cui1, Ethan Z Sy1, Adrija Mamidipalli1, Gavin Hamilton1, Scott B Reeder3, and Claude B Sirlin1

1Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, United States, 2Computational and Applied Statistics Laboratory, University of California San Diego, San Diego, CA, United States, 3Department of Radiology, Medical Physics, Biomedical Engineering, Medicine, and Emergency Medicine, University of Wisconsin Madison, Madison, WI, United States

As liver fat is heterogeneously distributed, longitudinal changes in liver fat may vary between liver segments. We used confounder-corrected chemical-shift-encoded MRI to examine longitudinal changes in proton density fat fraction (PDFF) of individual liver segments in obese adults following a weight-loss program comprising a very low calorie diet (VLCD) followed by bariatric weight loss surgery (WLS). We observed that changes in PDFF in the 5-month postoperative period vary across segments, with right-lobe segments having more rapid reduction in liver fat.

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