Meeting Banner
Abstract #0169

Towards Quantitative Cardiac First-Pass Perfusion Imaging using Hyperpolarized [13]-Urea

Maximilian Fuetterer1, Julia Busch1, Sophie M. Peereboom1, Lukas Wissmann1, Constantin von Deuster1, Nikola Cesarovic2, Miriam Lipiski2, Christian T. Stoeck1, and Sebastian Kozerke1

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2Division of Surgical Research, University Hospital Zurich, Zurich, Switzerland

Hyperpolarized [13C] urea perfusion imaging using velocity-selective excitation is qualitatively and semi-quantitatively compared with clinically used [1H] Gadolinium first-pass perfusion imaging in healthy pigs. Higher contrast-to-noise ratios and comparable sensitivity for semi-quantitative perfusion measures over myocardial sectors can be achieved with [13C] urea. Arterial input sampling in the ascending aorta using a second imaging slice with conventional excitation is proposed. Feasibility of accurate absolute myocardial blood flow quantification using [13C] urea is demonstrated.

This abstract and the presentation materials are available to members only; a login is required.

Join Here