Abstract #0181

Reduced Distortion in Diffusion Tensor MRI with Eddy Current Nulled Convex Optimized Diffusion Encoding (EN-CODE)

Eric Aliotta^1,2, Kevin Moulin¹, and Daniel B. Ennis^1,2

¹Department of Radiological Sciences, University of California, Los Angeles, CA, United States, ²Biomedical Physics IDP, University of California, Los Angeles, CA, United States

Eddy currents distort images and confound diffusion tensor reconstruction. In this work, convex optimized diffusion encoding (CODE) was extended to include an eddy current nulling term (EN-CODE) to achieve minimum TE diffusion tensor imaging (DTI) without eddy current distortions. EN-CODE was evaluated in simulations and through imaging in phantoms and healthy subjects. EN-CODE achieves distortion reduction on par with the existing twice refocused spin echo (TRSE) technique with a substantially shorter TE.

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