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Abstract #0187

PAM50: Multimodal template of the brainstem and spinal cord compatible with the ICBM152 space

Benjamin De Leener1, Vladimir Fonov2, D. Louis Collins2, Virginie Callot3,4, Nikola Stikov1,5, and Julien Cohen-Adad1,6

1NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada, 2Montreal Neurological Institute, McGill University, Montreal, QC, Canada, 3Aix-Marseille Univ, CNRS, CRMBM UMR 7339, Marseille, France, 4CEMEREM, Hopital de la Timone, Pôle d’imagerie médicale, AP-HM, Marseille, France, 5Montreal Heart Institute, Montreal, QC, Canada, 6Functional Neuroimaging Unit, CRIUGM, Université de Montréal, Montreal, QC, Canada

Template-based analysis of multi-parametric MRI data of the spinal cord sets the foundation for multi-center studies with minimum bias, thereby helping the discovery of new biomarkers of spinal-related diseases. In this study, we introduce a spinal cord MRI template, the PAM50, which is anatomically compatible with the ICBM152 brain template and uses the same coordinate system. The fusion of the PAM50 and ICBM152 templates facilitates group studies and multi-center studies of combined brain and spinal cord MRI and also allows the use of existing atlases of the brainstem compatible with the ICBM template.

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