The impact and transmission mechanisms of the cardiac arterial pressure wave into brain tissue are not fully understood. It is hypothesised that age-related arterial stiffening and increased CBF pulsatility leads to propagation of the arterial wave further down the vascular tree causing tissue damage. Here we quantify inflow ($$$S_0$$$) and displacement/oxygenation ($$$T_2^*$$$) induced fluctuations of the EPI-signal at the cardiac frequency. We relate the EPI-signal phase at the cardiac frequency to the fluctuations of $$$S_0$$$ and $$$T_2^*$$$ over the cardiac cycle in the arteries, veins and tissue.
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